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Colon tumor

Carcinoma

Glassy cell carcinoma

Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 15 October 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features
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● Rare in colon; more common in cervix
● Considered a poorly differentiated adenosquamous carcinoma

Case reports
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● hCG production (Am J Surg Pathol 1996;20:187)

Micro description
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● Moderate ground glass or finely granular cytoplasm
● Cell wall is PAS+ and distinct
● Enlarged nuclei with prominent nucleoli

Micro images
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Cervix:
   

Low power; high power

Differential diagnosis
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● Focal hCG producing adenocarcinoma: (more common)

End of Colon tumor > Carcinoma > Glassy cell carcinoma

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