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Colon tumor

Other

Grossing of colonic lesions


Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 2 May 2012, last major update May 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Diagrams
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Anatomic subsites

Polyps
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● Fix first for proper sectioning
● Take section through surgical margin of stalk (may want to ink first)
● Embed entirely to detect high grade dysplasia or invasive carcinoma (Am J Clin Pathol 2001;116:336)

Colectomy - no tumor
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● Remove mesentery and sample lymph nodes while fresh
● Either open bowel and pin overnight to fix, or inject specimen with formalin to fix

Take these sections:
● Abnormal areas by taking sections perpendicular to mucosal folds (through bowel wall)
● Resection margins
● Appendix, terminal ileum, cecum and ileocecal value, if present

Colectomy - tumor
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● Remove mesentery and dissect lymph nodes while fresh
● May use clearing agent to obtain sufficient number of lymph nodes (see staging)
● Either open bowel (donít cut through tumor) and pin overnight to fix, or inject specimen with formalin to fix

Take these sections:
● Tumor (entire tumor if 5 sections or less or 1 section per cm diameter)
● Serosa at point of deepest penetration of tumor (may want to ink serosa first)
● Full thickness of bowel wall (may need to split to fit into a cassette)
● Resection margins
● Appendix, terminal ileum, cecum and ileocecal value, if present
● Any abnormalities
● Normal appearing bowel

End of Colon tumor > Other > Grossing of colonic lesions


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