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Colon tumor

Mesenchymal tumors

Idiopathic retractile mesenteritis of colon

Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 29 September 2014, last major update April 2012
Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.


● Also called mesenteric panniculitis (Dis Colon Rectum 1987;30:962)
● Uncommon non-neoplastic idiopathic condition usually affecting small bowel, which can also cause thickening and shortening of colonic mesentery (JBR-BTR 2011;94:241)
● Common in rural areas of Peru (Rev Gastroenterol Peru 1998;18 Suppl 1:114), otherwise rare
● Usually men age 40+ years; associated with intestinal obstruction but no other systemic symptoms

Case reports

● 12 year old girl (Pediatr Radiol 1997;27:342)
● 40 year old man with large mesenteric mass (Arch Pathol Lab Med 2001;125:443)
● 46 year old woman (Surg Today 1996;26:435)

Gross description

● Markedly thickened and rubbery mesentery with twist of bowel

Gross images

Various images

Micro description

● Fibrosis with massive accumulation of dense collagen, fat necrosis, chronic inflammation especially around the vessels and variable focal calcification
● Minimal atypia, no / minimal mitotic figures
● Diagnosis based on H&E and excluding other disorders; no specific immunostains

Micro images

Various images

Dense collagen and chronic inflammatory cells

Infiltration of mesentery by foamy macrophages

Angiomatoid proliferation with microthrombi (figure 5)

Differential diagnosis

Idiopathic retroperitoneal fibrosis
Inflammatory myofibroblastic tumor
Liposarcoma (Chirurg 2001;72:742)
Lymphoma: sclerosing

End of Colon tumor > Mesenchymal tumors > Idiopathic retractile mesenteritis of colon

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