Colon tumor
Mesenchymal tumors
Kaposi sarcoma

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 14 February 2017, last major update February 2017

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Kaposi sarcoma colon

Cite this page: Kaposi sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorkaposi.html. Accessed March 29th, 2017.
Definition / General
  • Vascular malignancy caused by human herpes virus 8 (see topic in Soft tissue chapter)
Essential Features
  • Vascular malignancy most often seen in AIDS patients with HHV8 infection
  • Rare in gastrointestinal tract
Epidemiology
  • Most common gastrointestinal malignancy attributable to AIDS (Am J Gastroenterol 1991;86:715)
  • Currently rare; incidence decreased from use of HAART for AIDS treatment
Etiology
  • HHV8 infection
Clinical Features
Prognostic Factors
Case Reports
Treatment
  • Chemotherapy and radiation preferred over surgery
Clinical Images

Images hosted on other servers:

Kaposi sarcoma

Cherry red polyps on endoscopy

Gross Description
  • Reddish brown to purple macules or polyps, typically 0.5 - 1.5 cm
Micro Description
  • Lamina propria based lesion composed of spindle cells with mild to moderate atypia, arranged in vague fascicles and separated by slit-like vessels
  • Extravasated red blood cells common
  • PAS positive, diastase resistant hyaline globules sometimes seen
Micro Images

Images hosted on PathOut server:

Contributed by Dr. Raul Gonzalez, University of Rochester Medical Center (USA):

H&E, intermediate power

H&E, high power



Images hosted on other servers:

Low power

High power

CD34

Positive Stains
Negative Stains
Differential Diagnosis