Colon tumor
Mesenchymal tumors
Liposarcoma


Topic Completed: 1 May 2017

Revised: 9 July 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Colonic liposarcoma

Raul S. Gonzalez, M.D.
Page views in 2018: 310
Page views in 2019 to date: 316
Cite this page: Gonzalez R. Liposarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorliposarcoma.html. Accessed November 17th, 2019.
Definition / general
  • Rare adipocytic sarcoma primarily or secondarily involving the colon
Essential features
  • Rare and usually arises in the retroperitoneum or mesentery
  • Can be any subtype of liposarcoma
Terminology
  • Soft tissue terminology applies for tumor subtypes (well differentiated liposarcoma, myxoid liposarcoma, etc.)
Sites
  • Frequently arises in retroperitoneum, involving colon secondarily
Clinical features
  • Occurs across a wide age range
  • May cause abdominal pain or intussusception
Case reports
Treatment
  • Resection, radiotherapy
Clinical images

Images hosted on other servers:
Missing Image

CT of liposarcoma filling abdomen

Missing Image

Submucosal liposarcoma on colonoscopy

Missing Image

Liposarcoma removal during surgery

Gross description
  • Large mass that can involve other organs in addition to the colon
Gross images

Images hosted on other servers:
Missing Image

Tumor of pericolonic adipose tissue

Missing Image

Tumor replacing colon wall

Microscopic (histologic) description
  • Various subtypes; see soft tissue section for additional information
  • Dedifferentiated liposarcomas may resemble other mesenchymal tumors (such as GIST) but usually have foci of well differentiated liposarcoma
Microscopic (histologic) images

Contributed by Raul S. Gonzalez, M.D.
Missing Image

Well differentiated and dedifferentiated liposarcomas



Images hosted on other servers:
Missing Image

Well differentiated liposarcoma

Missing Image

Mixed-type liposarcoma

Missing Image

Dedifferentiated liposarcoma

Positive stains
Board review question #1
    Liposarcomas involving the gastrointestinal tract usually arise in what location?

  1. Extragastrointestinal
  2. Mucosa
  3. Muscularis propria
  4. Submucosa
  5. Subserosa
Board review answer #1
A. Extragastrointestinal

Reference: Colon tumor - Liposarcoma

Comment here
Back to top