Liposarcoma

Colon tumor
Mesenchymal tumors
Liposarcoma

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 2 June 2017, last major update May 2017

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Colonic liposarcoma

Table of Contents

Cite this page: Liposarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorliposarcoma.html. Accessed July 14th, 2017.

Definition / general

Rare adipocytic sarcoma primarily or secondarily involving the colon

Essential features

Rare and usually arises in the retroperitoneum or mesentery
Can be any subtype of liposarcoma

Terminology

Soft tissue terminology applies for tumor subtypes (well differentiated liposarcoma, myxoid liposarcoma, etc.)

Sites

Frequently arises in retroperitoneum, involving colon secondarily

Clinical features

Occurs across a wide age range
May cause abdominal pain or intussusception

Case reports

32 year old woman with Crohn’s disease and sigmoid liposarcoma causing intussusception (Rev Esp Enferm Dig 2016;108:591)
34 year old man with metabolic syndrome and well differentiated liposarcoma of colonic submucosa (J Clin Diagn Res 2015;9:OD01)
46 year old man with 12 cm subserosal myxoid liposarcoma (J Gastrointest Surg 2006;10:652)
71 year old female with 25 cm dedifferentiated liposarcoma of transverse colon (Int J Surg Case Rep 2014;5:8)

Treatment

Resection, radiotherapy

Clinical images

Images hosted on other servers:

CT of liposarcoma filling abdomen

Submucosal liposarcoma on colonoscopy

Liposarcoma removal during surgery

Gross description

Large mass that can involve other organs in addition to the colon

Gross images

Images hosted on other servers:

Tumor of pericolonic adipose tissue

Tumor replacing colon wall

Microscopic (histologic) description

Various subtypes; see soft tissue section for additional information
Dedifferentiated liposarcomas may resemble other mesenchymal tumors (such as GIST) but usually have foci of well differentiated liposarcoma

Microscopic (histologic) images

Images hosted on Pathout server: