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Colon tumor

Polyps

Lymphoid polyp

Reviewers: Shilpa Jain, M.D. (see Reviewers page)
Revised: 16 October 2011, last major update August 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.

Clinical features
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● Also called lymphoid hyperplasia
● All ages
● May be associated with bleeding or prolapse
● Has been reported in children with common variable immunodeficiency (Indian J Pathol Microbiol 2009;52:530) and selective IgA deficiency (Pol Merkur Lekarski 2008;24:449)
● Usually solitary, sessile and in rectum

Case reports
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● 8 year old boy with lymphoid hyperplasia throughout bowel (Z Gastroenterol 1997;35:271)
● 25 year old renal transplant patient with massive bleeding (Indian J Gastroenterol 1996;15:20)
● 51 year old woman (J Clin Pathol 1997;50:1034)

Treatment
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● Excision
● Chemotherapy for lymphoma has been useful

Gross description
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● Soft, superficial polyp covered by intact, smooth, gray mucosa
● Single or multiple

Micro description
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● Mucosal or submucosal lymphoid follicles with germinal centers that may distort muscularis mucosa or involve muscularis propria

Micro images
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Lymphoid follicles infiltrating throughout bowel wall


Reactive germinal center


Pseudolymphoma in a case with previous colon and gastric carcinoma

Differential diagnosis
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● Lymphoma: both B cell (Am J Gastroenterol 1999;94:2540) and T cell (Gastroenterology 1996;111:778)

End of Colon tumor > Polyps > Lymphoid polyp

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