Colon tumor
Lymphoma and hematopoietic lesions
Lymphoma - general

Topic Completed: 1 February 2012

Revised: 12 June 2019

Copyright: 2003-2019,, Inc.

PubMed Search: "Lymphoma of colon"

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Cite this page: Singh C. Lymphoma - general. website. Accessed August 24th, 2019.
Definition / general
  • Less common in colon than small bowel or stomach
  • Usually B cell lineage in Western countries
  • 18% - 30% are T cell lineage in Korea (Dig Dis Sci 2005;50:2243) and China (Zhonghua Bing Li Xue Za Zhi 2004;33:445)
  • T cell patients are younger, associated with perforation and poorer prognosis
  • Risk factors: transplants, ulcerative colitis and AIDS
  • Regional lymph nodes involved in 50% of cases
  • Advanced lesions may impair gut motility by destroying muscle wall
Gross description
  • Plaque-like expansion of mucosa / submucosa, bowel wall thickening, polyps ("multiple lymphomatoid polyposis" if multiple polyps throughout colon) or ulceration
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