Lymphoma and hematopoietic lesions
Lymphoma-general of colon
Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 25 February 2012, last major update February 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Less common in colon than small bowel or stomach
● Usually B cell lineage in Western countries
● 18-30% are T cell lineage in Korea (Dig Dis Sci 2005;50:2243) and China (Zhonghua Bing Li Xue Za Zhi 2004;33:445)
● T cell patients are younger, associated with perforation and poorer prognosis
● Risk factors: transplants, ulcerative colitis and AIDS
● Regional lymph nodes involved in 50% of cases
● Advanced lesions may impair gut motility by destroying muscle wall
● Plaque-like expansion of mucosa / submucosa, bowel wall thickening, polyps (“multiple lymphomatoid polyposis” if multiple polyps throughout colon) or ulceration
End of Colon tumor > Lymphoma and hematopoietic lesions > Lymphoma-general of colon
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