Colon tumor
Lymphoma and hematopoietic lesions
Lymphoma - general

Author: Charanjeet Singh, M.D. (see Authors page)

Revised: 3 January 2017, last major update February 2012

Copyright: (c) 2003-2017,, Inc.

PubMed Search: "Lymphoma of colon"
Cite this page: Lymphoma - general. website. Accessed November 15th, 2018.
Definition / general
  • Less common in colon than small bowel or stomach
  • Usually B cell lineage in Western countries
  • 18% - 30% are T cell lineage in Korea (Dig Dis Sci 2005;50:2243) and China (Zhonghua Bing Li Xue Za Zhi 2004;33:445)
  • T cell patients are younger, associated with perforation and poorer prognosis
  • Risk factors: transplants, ulcerative colitis and AIDS
  • Regional lymph nodes involved in 50% of cases
  • Advanced lesions may impair gut motility by destroying muscle wall
Gross description
  • Plaque-like expansion of mucosa / submucosa, bowel wall thickening, polyps ("multiple lymphomatoid polyposis" if multiple polyps throughout colon) or ulceration