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Cite this page: Lymphoma - general. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/colontumorlymphomageneral.html. Accessed July 14th, 2017.
Definition / general
- Less common in colon than small bowel or stomach
- Usually B cell lineage in Western countries
- 18% - 30% are T cell lineage in Korea (Dig Dis Sci 2005;50:2243) and China (Zhonghua Bing Li Xue Za Zhi 2004;33:445)
- T cell patients are younger, associated with perforation and poorer prognosis
- Risk factors: transplants, ulcerative colitis and AIDS
- Regional lymph nodes involved in 50% of cases
- Advanced lesions may impair gut motility by destroying muscle wall
Gross description
- Plaque-like expansion of mucosa / submucosa, bowel wall thickening, polyps ("multiple lymphomatoid polyposis" if multiple polyps throughout colon) or ulceration
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