Colon tumor
Lymphoma and hematopoietic lesions
Mantle cell lymphoma

Author: Charanjeet Singh, M.D. (see Authors page)

Revised: 14 August 2018, last major update February 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Mantle cell lymphoma colon

Cite this page: Singh, C. Mantle cell lymphoma. website. Accessed November 15th, 2018.
Definition / general
Case reports
Gross description
  • Nodular, sessile or polypoid lesions, widely spaced and confluent studded or cobblestone appearance
  • Each polyp 2 mm to 2 cm
  • May be dominant tumor mass in ileocecum
  • Endoscopically normal mucosa may have small tumor infiltrates also
Gross images

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Lymphomatoid polyposis

Microscopic (histologic) description
  • Mantle cells (small lymphocytes with pale cytoplasm and cleaved nuclei), often invasion of submucosa, proliferation around germinal centers and sparing of mucosa
  • Late epithelial invasion and ulceration
  • Note: may also be minute lymphoid infiltrates in known mantle cell patients
Microscopic (histologic) images

Images hosted on other servers:

Figures 2, 3A - 3D

Various images

Positive stains
Negative stains
Differential diagnosis