Colon tumor
Familial polyposis syndromes
Turcot syndrome

Author: Jennifer Findeis-Hosey, M.D. (see Authors page)
Editorial Board review: Raul Gonzalez, M.D.

Revised: 27 December 2016, last major update March 2016

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Turcot's syndrome [title]

Cite this page: Turcot syndrome. website. Accessed December 11th, 2018.
Definition / general
Essential features
  • Pronounced with silent second t (Turcot was French Canadian)
Clinical features
  • Same as FAP or Lynch Syndrome, but additionally with central nervous system tumor (as above)
Case reports
Differential diagnosis
  • Constitutional mismatch repair deficiency syndrome: biallelic mismatch repair gene mutation; patients develop brain tumors, hematopoietic malignancies and Lynch syndrome associated tumors (Haematologica 2010;95:699)
Additional references