Villous adenocarcinoma of colon
Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 1 August 2012, last major update January 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● 5% incidence in one study (World J Gastroenterol 1998;4:527)
● Pre-resection biopsies may not be diagnosed as carcinoma
● Appear to have a good prognosis
● May be associated with profound electrolyte disturbance (Ann Surg 1962;156:318)
Villous tumor with central ulceration
● Villous architecture in 50% or more
● Presence of epithelial islands in desmoplastic stroma is specific and 67% sensitive for carcinoma vs. adenoma (Am J Surg Pathol 2004;28:1460)
Contributed by Semir Vranic, M.D.
Abrupt transition from benign to malignant mucosa
End of Colon tumor > Carcinoma > Villous adenocarcinoma of colon
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).