Middle ear, inner ear and temporal bone tumors - malignant

Author: Nat Pernick, M.D. (see Authors page)

Revised: 20 February 2018, last major update October 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Adenocarcinoma [title] ear

Cite this page: Pernick, N. Adenocarcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/earadenocarcinoma.html. Accessed October 17th, 2018.
Definition / general
  • Extremely rare; arises from middle ear mucosa
  • Not associated with chronic otitis media
  • May fill middle ear space and encase ossicles
  • Chronic progressive hearing loss and unilateral otorrhea
  • Tumor may perforate tympanic membrane and present as external auditory canal mass
  • Slow growing, locally aggressive, doesn't metastasize but may exhibit intracranial extension (J Neurosurg 1999;90:555)
  • Complete excision
Microscopic (histologic) description
  • Resembles adenoma but with increased pleomorphism and mitotic figures and extensive infiltration of surrounding structures
Differential diagnosis
  • Metastases: need good clinical history to rule out