Inflammatory / infectious / autoimmune / systemic disorders

Author: Nat Pernick, M.D. (see Authors page)

Revised: 8 February 2018, last major update October 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Ear malakoplakia

Cite this page: Pernick, N. Malakoplakia . PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/earmalakoplakia.html. Accessed October 20th, 2018.
Definition / general
  • Rarely occurs in middle ear
  • Due to inability of histiocytes to ingest bacteria such as E. coli with accumulation in phagolysosomes
Case reports
Microscopic (histologic) description
  • Sheets of histiocytes with eosinophilic, granular to vacuolated cytoplasm (Hansemann cells), lymphocytes, plasma cells, neutrophils
  • Diagnostic feature is intracytoplasmic or extracellular calcospherites (Michaelis-Gutmann bodies)
Microscopic (histologic) images

Images hosted on other servers:
Missing Image

Various images - not ear

Positive stains