Other nonneoplastic
Atypical regenerative hyperplasia

Topic Completed: 1 November 2012

Minor changes: 9 September 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Atypical regenerative hyperplasia esophageal

Elliot Weisenberg, M.D.
Page views in 2019: 1,338
Page views in 2020 to date: 799
Cite this page: Weisenberg E. Atypical regenerative hyperplasia. website. Accessed August 10th, 2020.
Definition / general
  • Associated with chronic esophagitis, not neoplasia
  • Also called reactive hyperplasia, pseudoepitheliomatous hyperplasia
Microscopic (histologic) description
  • Architectural uniformity of immature and relatively monotonous sized small / medium keratinocytes mixed with inflammatory cells
  • Pleomorphism and atypia are common in keratinocytes and endothelial cells
  • Also mitotic figures
  • No cytoarchitectural pleomorphism, no desmoplasia
Microscopic (histologic) images

Images hosted on other servers:

Squamous cell
carcinoma vs.
atypical regenerative

Various images

Differential diagnosis
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