Esophagus
Miscellaneous
Features to report for esophageal carcinoma

Author: Feriyl Bhaijee, M.D. (see Authors page)
Editor: Israh Akhtar, M.D.

Revised: 1 February 2018, last major update December 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Features to report esophageal carcinoma[TIAB]

Cite this page: Bhaijee, F. Features to report for esophageal carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/esophagusfeatures.html. Accessed May 24th, 2018.
Definition / general
  • Editorial note
  • Lymphomas, well differentiated neuroendocrine (carcinoid) tumors and sarcomas should be reported using separate TNM staging systems or CAP protocols
Biopsy
  • Specimen type (procedure)
  • Site of biopsy (if known)
  • Histologic type
  • Histologic grade
  • Microscopic tumor extension
  • Additional findings
Endoscopic resection, esophagectomy or esophagogastrectomy
  • Specimen
    • Esophagus
    • Proximal stomach
    • Other (specify)
    • Not specified
  • Procedure
    • Endoscopic resection
    • Esophagectomy
    • Esophagogastrectomy
    • Other (specify)
    • Not specified
  • Tumor site
    • Cervical (proximal) esophagus
    • Midesophagus
      • Upper thoracic esophagus
      • Mid thoracic esophagus
    • Distal (lower thoracic) esophagus
    • Esophagogastric junction (EGJ)
    • Proximal stomach and EGJ
    • Other (specify)
    • Not specified
  • Relationship of tumor to esophagogastric junction (EGJ)
    • Tumor is confined to the tubular esophagus and does not involve the EGJ
    • Tumor midpoint is in the distal esophagus and tumor involves the EGJ
    • Tumor midpoint is at the EGJ
    • Tumor midpoint is in the proximal stomach or cardia and tumor involves the EGJ
    • Not specified
    • Cannot be assessed
    • Distance of tumor center from EGJ (if applicable): __ cm
  • Tumor size
    • Greatest dimension: __ cm
    • Cannot be determined
  • Histologic type
    • Squamous cell carcinoma
    • Adenocarcinoma
    • Adenosquamous carcinoma
    • High grade neuroendocrine carcinoma
      • Large cell neuroendocrine carcinoma
      • Small cell neuroendocrine carcinoma
    • Undifferentiated carcinoma
    • Other (specify)
    • Carcinoma, type cannot be determined
  • Histologic grade
    • Not applicable
    • GX: cannot be assessed
    • G1: well differentiated
    • G2: moderately differentiated
    • G3: poorly differentiated
    • G4: undifferentiated
  • Microscopic tumor extension
    • Cannot be assessed
    • No evidence of primary tumor
    • High grade dysplasia (carcinoma in situ)
    • Tumor invades lamina propria
    • Tumor invades muscularis mucosae
    • Tumor invades submucosal
    • Tumor invades muscularis propria
    • Tumor invades through muscularis propria into periesophageal soft tissue (adventitia)
    • Tumor directly invades adjacent structures (specify)
  • Margins
    • If all margins uninvolved by invasive carcinoma:
      • Distance of invasive carcinoma from closest margin: __ cm
      • Specify margin
    • Proximal / distal margin involved by:
      • Invasive carcinoma
      • Dysplasia
        • Squamous dysplasia: low / high grade
        • Intestinal metaplasia (Barrett esophagus) with dysplasia: low / high grade
      • Intestinal metaplasia (Barrett esophagus) without dysplasia
    • Circumferential (adventitial / deep) margin
      • Cannot be assessed
      • Uninvolved by invasive carcinoma
      • Involved by invasive carcinoma
    • Other margins (specify)
  • Treatment effect (carcinomas treated with neoadjuvant therapy, Dis Esophagus 2006;19:329)
    • No prior treatment
    • Present
      • No residual tumor (complete response, grade 0)
      • Marked response (minimal residual cancer, grade 1)
      • Moderate response (grade 2)
    • No definite response (poor / no response, grade 3)
    • Treatment history not known
  • Lymph vascular invasion
    • Not identified
    • Present
    • Indeterminate
  • Perineural invasion
    • Not identified
    • Present
    • Indeterminant
  • Pathologic staging (pTNM)
    • TNM descriptors
      • m (multiple primary tumors)
      • r (recurrent)
      • y (posttreatment)
    • Primary tumor (pT)
    • Regional lymph nodes (pN)
    • Distant metastasis (pM)
  • Additional pathologic findings
    • None
    • Intestinal metaplasia (Barrett esophagus)
    • Dysplasia: low / high grade
    • Esophagitis
    • Gastritis
    • Other (specify)
  • Ancillary studies (specify)
  • Clinical history
    • Barrett esophagus
    • Other (specify)
    • Not known
Optional features to report
Diagrams / tables

Images hosted on other servers:

Esophageal cancer staging