Esophagus
Other nonneoplastic
Glycogenic acanthosis


Topic Completed: 1 November 2012

Minor changes: 9 September 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Glycogenic acanthosis esophagus


Elliot Weisenberg, M.D.
Page views in 2019: 4,862
Page views in 2020 to date: 2,579
Cite this page: Weisenberg E. Glycogenic acanthosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/esophagusglycogenic.html. Accessed August 10th, 2020.
Definition / general
Gross description
  • Multiple white mucosal plaques < 1 cm; may resemble leukoplakia; polypoid lesions may occur in syndromic patients
Gross images

AFIP images

Numerous white islands

Slightly elevated longitudinal plaque



Images hosted on other servers:

White nodules

Microscopic (histologic) description
  • Epithelial thickening by large squamous cells of prickle cell layer packed with glycogen; no atypia, no inflammation
Microscopic (histologic) images

AFIP images
     

Thickened superficial squamous
epithelium with enlarged
squamous cells containing abundant
pale to clear cytoplasm


 Contributed by Dr. Mark R. Wick

Glycogen patch

Glycogen patch undigested PAS stain

Glycogen patch digested PAS stain



Images hosted on other servers:

Large squamous cells with abundant cytoplasm

Positive stains
  • PAS (glycogen), diastase sensitive
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