Reviewer: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 14 June 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Also called inflammatory esophagogastric polyp
- Similar descriptions in literature for inflammatory and hyperplastic polyp
- Uncommon, but most common esophageal polyp, near gastroesophageal junction
- May represent an exaggerated mucosal response to esophageal injury, including reflux associated ulceration and repair, protracted vomiting, Crohn’s disease, sclerotherapy for varices, heterotopic gastric mucosa, embedded pills, infection, anastomosis
- Usually men
- 48% associated with GERD; 15% with Barrett’s esophagus; not associated with carcinoma (Am J Surg Pathol 2011;35:1038)
- Hyperplastic gastric-type foveolar epithelium or squamous epithelium with granulation tissue, edematous lamina propria, inflammatory infiltrate; 67% have ulceration or erosion (Am J Surg Pathol 2001;25:1180)
- Squamous hyperplastic polyps may be inverted squamous papillomas, possibly HPV+ (Am J Surg Pathol 1993;17:803)
Various images (pdf)
End of Esophagus > Benign tumors > Hyperplastic polyp
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