Lacerations (Mallory-Weiss syndrome)
Reviewer: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 14 June 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Longitudinal tears at GE junction or proximal gastric mucosa from failure of reflex relaxation of muscularis of gastric outlet preceeding an antiperistaltic wave (eMedicine)
- Usually due to severe retching associated with alcoholism; also hyperemesis gravidarum, occasionally in weight lifters
- Tears may be mucosal or full-thickness
- Cause 5-10% of upper GI bleeds, usually limited, surgery not necessary
- Rarely causes sudden unexpected death (Arch Kriminol 2002;209:36, Srp Arh Celok Lek 2001;129:257, J Clin Pathol 1991;44:787)
- Boerhaave syndrome: esophageal rupture, usually lethal
- Support; vasoconstrictors, transfusions, occasionally balloon tamponade, surgical repair if possible
Laceration at GE junction
End of Esophagus > Non-neoplastic disorders > Lacerations (Mallory-Weiss syndrome)
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