Esophagus
Carcinoma
Lymphoepithelioma-like carcinoma


Topic Completed: 1 October 2013

Revised: 27 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Lymphoepithelioma-like carcinoma esophagus

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Cite this page: Weisenberg E. Lymphoepithelioma-like. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/esophaguslymphoepithelioma.html. Accessed May 23rd, 2019.
Definition / general
  • Rare primary esophageal malignancy with same histologic appearance as undifferentiated nonkeratinizing carcinoma of nasopharynx
  • May have better prognosis than other carcinomas
Terminology
Epidemiology
  • Very rare; most reports from Japan
Pathophysiology
Clinical features
  • Generally similar to squamous cell carcinoma; in one report presented like leiomyoma with nonprogressive course
Diagnosis
  • Endoscopic biopsy
Prognostic factors
  • In some case reports and anecdotally from reports in stomach, likely better prognosis than conventional adenocarcinoma or squamous cell carcinoma
Case reports
Treatment
  • Naspharyngeal carcinoma is treated with radiation therapy
Clinical images

Images hosted on other servers:

Elevated tumor

Microscopic (histologic) description
  • Variable numbers of primitive epithelial cells with lymphocytic infiltrate with variable plasma cells
Microscopic (histologic) images

Images hosted on other servers:

Located under squamous epithelium

Various immunostains

EBV associated molecules

Lymphocytic markers

Positive stains
Differential diagnosis
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