Esophagus
Premalignant lesions
Polypoid dysplasia


Topic Completed: 1 May 2013

Revised: 25 February 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Polypoid dysplasia esophagus


Elliot Weisenberg, M.D.
Page views in 2018: 496
Page views in 2019 to date: 534
Cite this page: Weisenberg E. Polypoid dysplasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/esophaguspolypoiddysplasia.html. Accessed October 22nd, 2019.
Definition / general
  • Found within Barrett esophagus, resembles colonic adenoma (well defined sessile or pedunculated polyp, usually 0.5 - 1.5 cm) but often associated with invasive adenocarcinoma (Hum Pathol 1999;30:745) so recommended to not use "adenoma" terminology; may resemble dysplasia in ulcerative colitis
  • 2% of all dysplasia seen in Barrett esophagus
  • Clinical, pathological and molecular features are similar to flat Barrett dysplasia, less often has a pyloric gland phenotype (Virchows Arch 2005;446:537)
Case reports
Gross description
  • Well defined sessile or pedunculated polypoid lesion, 4 to 15 mm
Microscopic (histologic) description
  • Adenocarcinoma may be present within polyp
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