Benign tumors

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 18 January 2018, last major update February 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Schwannoma esophagus

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Page views in 2019 to date: 15
Cite this page: Weisenberg, E. Schwannoma. website. Accessed January 21st, 2019.
Definition / general
Case reports
  • Excision, does not recur
Microscopic (histologic) description
  • Well circumscribed, composed of interlacing bundles of spindle cells interspersed with collagenous strands, scattered inflammatory cells with peripheral cuff of lymphoid aggregates, often PAS+ crystalloids; may exhibit nuclear atypia
  • No mitotic figures, no epithelioid features, no skenoid fibers
Microscopic (histologic) images

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Melanin pigment

Positive stains
Electron microscopy images

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Melanosomes at various stages of maturation

Premelanosomes stages II to IV

Differential diagnosis