Topic Completed: 1 March 2013

Minor changes: 25 September 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Ataxia-telangiectasia [title] eye

Deepali Jain, M.D.
Page views in 2019: 217
Page views in 2020 to date: 105
Cite this page: Jain D. Conjunctiva: ataxia-telangiectasia. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeataxia.html. Accessed May 29th, 2020.
Definition / general
  • Autosomal recessive disease; previously called Louis-Bar syndrome
  • Characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia and recurrent respiratory and sinus infections
  • Telangiectatic blood vessels in bulbar conjunctiva in > 90% (Am J Ophthalmol 2002;134:891), mostly confined to palpebral fissures, sausage shaped aneurysmal dilatation with abrupt turns
  • Mostly visible by age 4 - 5 years, primarily within palpebral fissure (Acta Ophthalmol Scand 2007;85:557)
  • Patients develop ocular motor apraxia (Acta Ophthalmol Scand 2007;85:557)
Clinical images

Images hosted on other servers:
Missing Image

Nasal part of conjunctiva

Missing Image

Telangiectasias in ear with conjunctival telangiectasias

Microscopic (histologic) images

Images hosted on other servers:
Missing Image

staining of conjunctival
Back to top