Eye
Eyelid inflammatory disorders
Chalazion of eyelid

Author: Nat Pernick, M.D. (see Authors page)

Revised: 3 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Chalazion [title] of eyelid

Cite this page: Pernick, N. Eyelid: chalazion of eyelid. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyechalazion.html. Accessed December 17th, 2018.
Definition / general
  • Very common
  • Deep seated lipogranuloma that develops near meibomian glands or glands of Zeis
  • Probably due to obstruction and nonspecific inflammation (blepharitis), leading to discharge of sebaceous material into surrounding tissue and resulting intense granulomatous inflammatory reaction
  • May erupt through conjunctival surface of eyelid
  • Initial specimens are often not submitted for pathologic examination but recurrences suggest sebaceous carcinoma and should be examined
Treatment
  • Curettage
Microscopic (histologic) description
  • Multiple foci of granulomatous inflammation with microabscesses and multinucleated giant cells
  • Center of granulomas may contain small fat globules
Microscopic (histologic) images

Images hosted on other servers:
Missing Image

Chalazion

Differential diagnosis