Cicatrizing conjunctivitis

Author: Deepali Jain, M.D. (see Authors page)

Revised: 7 November 2018, last major update September 2013

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Cicatrizing conjunctivitis

Cite this page: Jain, D. Conjunctiva: cicatrizing conjunctivitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyecicatrizingconj.html. Accessed November 21st, 2018.
Definition / general
  • Cicatrizing: causing a scar and possibly affecting vision
  • Conjunctival fibrosis due to chronic inflammation, leading to alterations of conjunctival architecture
Clinical features
  • Dry eyes
  • Loss of transparency and vision
  • Positive direct immunofluorescence with IgA, IgM, IgG, complement C3, complement C4, and fibrinogen in autoimmune diseases
  • Medical management varies according to specific causes
Microscopic (histologic) description
  • Fibrosis and inflammation consisting of neutrophils, lymphocytes, plasma cells
  • Keratinization of superficial layer, hyperplasia of basal layers