Eye
Conjunctiva
TNM staging (clinical) for melanoma of the conjunctiva


Topic Completed: 1 September 2013

Revised: 27 March 2019

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PubMed Search: TNM staging for melanoma of the conjunctiva clinical

Related Topics: Pathologic staging

Nat Pernick, M.D.
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Cite this page: Pernick N. Conjunctiva: TNM staging (clinical) for melanoma of the conjunctiva. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeconjTNMmelanomaclinical.html. Accessed December 13th, 2019.

TNM staging (clinical) of melanoma of the conjunctiva, AJCC 7th edition
Primary tumor (T)
  • TX: Primary tumor cannot be assessed
  • T0: No evidence of primary tumor
  • T(is): Melanoma confined to the conjunctival epithelium
  • Malignant conjunctival melanoma of the bulbar conjunctiva
    • T1a: Less than or equal to 1 quadrant
    • T1b: More than 1 but less than or equal to 2 quadrants
    • T1c: More than 2 but less than or equal to 3 quadrants
    • T1d: Greater than 3 quadrants
  • Malignant conjunctival melanoma of the nonbulbar conjunctiva (palpebral, forniceal caruncular)
    • T2a: No caruncular, less than or equal to 1 quadrant
    • T2b: No caruncular, greater than 1 quadrant
    • T2c: Any caruncular, with less than or equal to 1 quadrant
    • T2d: Any caruncular, with greater than 1 quadrant
  • Any malignant conjunctival melanoma with local invasion
    • T3a: Globe
    • T3b: Eyelid
    • T3c: Orbit
    • T3d: Sinus
    • T4: Tumor invades the central nervous system

  • Quadrants are defined by clock hour, starting at the limbus (e.g., 6, 9, 12, 3) extending from the central corneal, to and beyond the eyelid margins
  • This will bisect the caruncle
Regional lymph nodes (N)
  • NX: Regional lymph nodes cannot be assessed
  • N0a (biopsied): No regional lymph node metastasis, biopsy performed
  • N0b (biopsied): No regional lymph node metastasis, biopsy not performed
  • N1: Regional lymph node metastasis
Distant metastasis (M)
  • M0: No distant metastasis
  • M1: Distant metastasis
Stage grouping
  • No stage grouping is presently recommended by AJCC
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