Chronic actinic keratopathy

Topic Completed: 1 October 2013

Revised: 27 March 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Chronic actinic keratopathy

Nat Pernick, M.D.
Page views in 2018: 240
Page views in 2019 to date: 192
Cite this page: Pernick N. Cornea: chronic actinic keratopathy. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyecorneachronicactinickeratopathy.html. Accessed October 17th, 2019.
Definition / general
  • Also called climatic droplet keratopathy or spheroidal degeneration
  • Initially involves periphery of cornea, increases in severity and incidence with age
  • Associated with long term exposure to excessive ultraviolet light
Microscopic (histologic) description
  • Amorphous globules of protein accumulate in superficial stroma of interpalpebral portion of cornea
Differential diagnosis
  • Other disorders produce similar globules
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