Eye
Cornea
Graft failure of cornea


Topic Completed: 1 October 2013

Revised: 27 March 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Graft failure of cornea [title]

Nat Pernick, M.D.
Page views in 2018: 546
Page views in 2019 to date: 420
Cite this page: Pernick N. Cornea: graft failure of cornea. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyecorneagraftfailure.html. Accessed August 23rd, 2019.
Definition / general
  • Most corneal transplants are successful and provide long term improvement in visual acuity
  • Matching of donor and recipient tissue is not necessary for corneal transplants since no lymphatics or blood vessels in corneal stroma
  • Graft failure may be due to surgical damage of endothelium, immunologic rejection (uncommon) or recurrence of dystrophy
Microscopic (histologic) description
  • Fibrosis, vascularization, inflammatory cell infiltrate
  • Full thickness scars from prior surgery are present at edge of specimen
  • 50% have fibrous retrocorneal membrane
Back to top