Ephelides or freckle

Author: Deepali Jain, M.D. (see Authors page)

Revised: 18 April 2018, last major update March 2013

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Ephelides or freckle [title] conjunctiva

Cite this page: Jain, D. Conjunctiva: ephelides or freckle. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeephelis.html. Accessed November 17th, 2018.
Definition / general
  • Congenital pigmentation, does not evolve into melanoma
  • Surrounding conjunctiva is normal
  • Associated with fair skin, red hair, Carney syndrome
Gross description
  • Flat pigmented foci
Microscopic (histologic) description
  • Well circumscribed area of hyperpigmented basal cells
Microscopic (histologic) images

Images hosted on PathOut server:
Missing Image

Increased melanocytic
activity in basal layer