Eyelid other tumors
Squamous cell carcinoma of eyelid

Author: Nat Pernick, M.D. (see Authors page)

Revised: 8 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Squamous cell carcinoma [title] eyelid [title]

Page views in 2018: 287
Page views in 2019 to date: 35
Cite this page: Pernick, N. Eyelid: squamous cell carcinoma of eyelid. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeeyelidscc.html. Accessed January 23rd, 2019.
Definition / general
  • 10% of carcinomas in eyelid
  • Usually lower lid
  • Rarely are adenoid (pseudoglandular)
  • Rarely invade eye or orbit or metastasize
Gross description
  • Elevated and thickened areas of eyelid, may be ulcerated or friable
Microscopic (histologic) description
  • Invasion of malignant squamous cells into dermis
  • Cells are large and eosinophilic with marked atypia
  • Often abnormal deep keratinization, may have keratin pearls
Microscopic (histologic) images

Images hosted on PathOut server:

Squamous cell carcinoma - spindle cell type
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Atrophic epidermis over a highly infiltrative tumor

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Spindled cells resemble sarcoma