Eye
Eyelid
Other tumors
Seborrheic keratosis


Topic Completed: 1 February 2014

Minor changes: 29 June 2020

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Seborrheic keratosis [title] eyelid

Nat Pernick, M.D.
Page views in 2019: 1,031
Page views in 2020 to date: 570
Cite this page: Pernick N. Seborrheic keratosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeeyelidseborrheickeratosis.html. Accessed July 13th, 2020.
Gross description
  • Elevated irregular lesions, often crusty or greasy appearing
  • Often pigmented
Microscopic (histologic) description
  • Acanthosis with marked hyperkeratosis and keratin filled cysts
  • Also increased pigmentation in basal layer
  • No atypia
Microscopic (histologic) images

AFIP images
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Plaque-like lesion with cords of basaloid
cells and numerous horn cysts

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Irritated seborrheic keratosis (inverted follicular
keratosis) has acanthotic epithelium with massive
hyperkeratosis forming a cutaneous horn; numerous
squamous eddies within acanthotic epithelium

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