Acute inflammation of globe

Author: Nat Pernick, M.D. (see Authors page)

Revised: 9 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Acute inflammation [title] globe

Related Topics: Chronic inflammation of globe (nongranulomatous), Granulomatous inflammation of globe

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Table of Contents
Cite this page: Pernick, N. Globe: acute inflammation of globe. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeglobeinflammation.html. Accessed January 23rd, 2019.
  • Usually infectious (bacteria or fungi, usually post-traumatic, also from intravenous drug use or hematogenous spread of infection)
  • Noninfectious cause is massive necrosis of uveal melanoma or metastatic carcinoma
  • Cataract surgery may cause mild endophthalmitis due to Propionibacterium acnes
  • Initially endophthalmitis (affects intraocular contents including vitreous humor but not sclera or cornea) - massive purulent reaction in anterior and vitreous chambers
  • Later panophthalmitis (involvement of retina, choroid, sclera or orbit)
  • Panophthalmitis exposes orbit to microorganisms but endophthalmitis does not
  • Late complication is Phthisis bulbi