Eye
Lacrimal duct / gland
Adenoid cystic carcinoma of lacrimal gland

Author: Nat Pernick, M.D. (see Authors page)

Revised: 9 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Adenoid cystic carcinoma [title] lacrimal gland

Cite this page: Pernick, N. Lacrimal duct: adenoid cystic carcinoma of lacrimal gland. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyelacrimaladenoidcystic.html. Accessed September 22nd, 2018.
Definition / general
  • 20 - 30% of lacrimal gland tumors
  • Most common malignant tumor of lacrimal gland
  • Aggressive, may infiltrate eyelid or brain
Radiology images

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Serrated borders indicating infiltrative growth

Microscopic (histologic) description
  • Basaloid growth with cribriform change
  • Relatively bland cytology
  • Perineural invasion, focal tumor necrosis
Microscopic (histologic) images

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Infiltration of orbit

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Basaloid pattern

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Cribriform pattern


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Cylindromatous or sclerosing pattern

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Perineural invasion

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Metastasis to lung



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Classic pattern