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Eye
Conjunctiva
Nevi

Reviewer: Deepali Jain, M.D. (see Reviewers page)
Revised: 13 October 2014, last major update March 2013
Copyright: (c) 2004-2014, PathologyOutlines.com, Inc.

See subtypes below: blue nevus, inflammatory juvenile conjunctival nevus, Spitz nevus

General
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Case reports
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Treatment
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Clinical images
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Various images
Balloon cell nevus
Variations in pigmentation
Variations in size
Variations in associated clinical features
Variations in location
Variations in clinical appearance
Change in nevus appearance over time
Gross description
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Micro description
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Micro images
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Benign nevus (B), amelanotic
nevus (C)
Conjunctival nevi
Epithelioid cell (clonal or inverted) nevi
Granular cell nevus

Subepidermal (A), compound (B),
cystic (C), intraepithelial (D),
and juvenile (E&F)
Compound nevus-variability in cytology

Atypical compound nevus-melanocytes in junctional area mature into
smaller and less hyperchromatic cells as they extend deeper into lamina propria
Balloon cell:
Various images
Balloon cell compound nevus
composed of large clear cells
Cystic compound nevus:
Figure 1
Figure 2
Figure 3
Figure 4
Fig 1: Multiple large cysts
Fig 2: Nevoid cells in junctional area around cystic spaces
Fig 3: Sheets of melanocytes with variable-sized cysts
Fig 4: Diffuse proliferation of melanocytes, with cysts lined by conjunctival epithelium with goblet cells

Positive stains
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Differential diagnosis
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Additional references
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Blue nevus (cellular blue nevus)
General
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Case reports
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Clinical images
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Movable, diffuse, blue-black lesion
Gross description
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Micro description
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Micro images
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Combined nevus: pigmented dendritic and spindled blue nevus cells in area adjacent to nevocytic foci
Various images
Conjunctival blue nevus
Composed of plump, heavily pigmented melanocytes
Focus of malignant transformation



Inflammatory juvenile conjunctival nevus
General
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Treatment
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Micro description
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Micro images
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Various images
Nerve growth factor and eosinophils
IHC for NGF and eosinophils
Differential diagnosis
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Additional references
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Spitz nevus
General
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Case reports
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Clinical images
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Lesion of eyelid
Gross description
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Micro description
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Micro images
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Lesion of eyelid
Positive stains
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Differential diagnosis
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End of Eye > Conjunctiva > Nevi


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