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General
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- Resembles solitary fibrous tumor but prominent vessels
- 30% recur, 15% metastasize (lung, liver, bone, regional lymph nodes), usually late
- Histology does not predict behavior (Hum Pathol 1982;13:210)
Case reports
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Micro description
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- Usually encapsulated
- Random pattern of polygonal and rounded cells with ill defined cytoplasm, variable nucleoli
- Staghorn vascular pattern and perivascular collagen, dense pericellular reticulin, occasional mitotic figures
- Must rule out other tumors with this pattern
Micro images
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Small polyhedral cells surround vascular spaces
Vascular channels have a staghorn pattern
Cells are polyhedral and spindled, with mild atypia
Metastatic liver nodule
A-large left orbital mass; B-random pattern of polygonal and rounded cells C-large and small vessels with staghorn pattern; D-reticulin densely surrounds each cell
Positive stains
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- CD34 (focal or weak), dense pericellular reticulin staining, vimentin
- Variable XIIIa
Negative stains
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- EMA, GFAP, S100, keratin, desmin, muscle specific actin, smooth muscle actin
Differential diagnosis
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End of Eye > Orbit and optic nerve > Hemangiopericytoma of orbit
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