Cite this page: Pernick N. Orbit and optic nerve: idiopathic sclerosing inflammation of orbit. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeorbitidiopathicsclerosing.html. Accessed June 1st, 2020.
Definition / general
- Insidious, chronic and progressive fibrosing process
- Damages orbital structures by entrapment and mass effect
- May have cell mediated pathogenesis, similar to retroperitoneal fibrosis (Mod Pathol 1993;6:581)
Microscopic (histologic) description
- Desmoplasia, sparse lymphocytes (usually T cells), histiocytes, plasma cells, neutrophils, eosinophils