Orbit and optic nerve
Metastases / spread to orbit

Topic Completed: 1 February 2014

Minor changes: 19 February 2020

Copyright: 2004-2020, PathologyOutlines.com, Inc.

PubMed Search: Metastases [title] orbit

Nat Pernick, M.D.
Page views in 2019: 93
Page views in 2020 to date: 21
Cite this page: Pernick N. Orbit and optic nerve: metastases / spread to orbit. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeorbitmetastases.html. Accessed May 29th, 2020.
Definition / general
  • Rarely is initial manifestation of childhood acute leukemia or adult carcinoma of breast, bronchus, kidney or prostate
  • Neuroblastoma and carcinoid tumor of lung or small bowel commonly metastasize to orbit (Hum Pathol 1982;13:459)
  • Primary embryonal rhabdomyosarcoma or carcinoid tumor of orbit may erroneously be interpreted as metastatic tumor
Clinical images

AFIP images
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Paranasal sinus carcinoma involving orbit

Gross images

AFIP images
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Paranasal sinus
carcinoma invades
nasal orbit

Microscopic (histologic) images

AFIP images
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Histiocytoid breast
carcinoma infiltrating
extraocular muscle

Images hosted on other servers:
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Fig 8: metastatic neuroblastoma

Differential diagnosis
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