Eye
Orbit & optic nerve
Solitary fibrous tumor-orbit


Topic Completed: 1 February 2014

Minor changes: 27 June 2020

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PubMed Search: solitary fibrous tumor orbit

Nat Pernick, M.D.
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Cite this page: Pernick N. Solitary fibrous tumor-orbit. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeorbitsft.html. Accessed September 29th, 2020.
Definition / general
Prognosis and treatment
  • 30% recur, 15% metastasize (lung, liver, bone, regional lymph nodes), usually late
  • Histology does not predict behavior (Hum Pathol 1982;13:210)
Radiology images

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MRI of right orbital tumor

Case reports
Microscopic (histologic) description
  • Usually encapsulated
  • Random pattern of polygonal and rounded cells with ill defined cytoplasm, variable nucleoli
  • Staghorn vascular pattern and perivascular collagen, dense pericellular reticulin, occasional mitotic figures
  • Must rule out other tumors with this pattern
Microscopic (histologic) images

AFIP images
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Small polyhedral cells surround vascular spaces

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Vascular channels have a staghorn pattern

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Cells are polyhedral and spindled, with mild atypia

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Metastatic liver nodule


Positive stains
Differential diagnosis
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