Toxoplasmosis of retina

Topic Completed: 1 February 2014

Minor changes: 5 April 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Toxoplasmosis[title] retina

Nat Pernick, M.D.
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Cite this page: Pernick N. Retina: toxoplasmosis of retina. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeretinatoxolasmosis.html. Accessed June 1st, 2020.
Definition / general
  • Common as an entity, rare in surgical specimens
  • May be due to reactivation of congenital infection
  • Diffuse retinal necrosis is associated with AIDS
  • Fundoscopy: optic nerve appears as "headlight in fog", leading to large scar
Microscopic (histologic) description
  • Focal areas of coagulative necrosis in retina, surrounded by granulomatous inflammation of choroid and sclera
  • Scar shows abrupt transition of normal retina to scarring with extension disruption of retina, retinal pigment epithelium and choroid with marked disruption of pigment
  • Cysts of Toxoplasma gondii within necrotic retina
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