Toxoplasmosis of retina

Author: Nat Pernick, M.D. (see Authors page)

Revised: 22 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Toxoplasmosis[title] retina

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Cite this page: Pernick, N. Retina: toxoplasmosis of retina. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeretinatoxolasmosis.html. Accessed January 23rd, 2019.
Definition / general
  • Common as an entity, rare in surgical specimens
  • May be due to reactivation of congenital infection
  • Diffuse retinal necrosis is associated with AIDS
  • Fundoscopy: optic nerve appears as "headlight in fog", leading to large scar
Microscopic (histologic) description
  • Focal areas of coagulative necrosis in retina, surrounded by granulomatous inflammation of choroid and sclera
  • Scar shows abrupt transition of normal retina to scarring with extension disruption of retina, retinal pigment epithelium and choroid with marked disruption of pigment
  • Cysts of Toxoplasma gondii within necrotic retina