Tumor features to report - retinoblastoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 22 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Tumor features retinoblastoma

Table of Contents
Definition / general
Cite this page: Pernick, N. Retina: tumor features to report - retinoblastoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeretinatumorfeatures.html. Accessed October 20th, 2018.
Definition / general
  • Editorial note
  • Tumor location
  • Number, size and location of lesion(s)
  • Differentiation (poorly differentiated, Flexner-Wintersteiner rosettes, Homer-Wright rosettes, fleurettes)
  • Growth pattern (diffuse, unifocal, multifocal)
  • Extraocular extension or choroidal invasion
  • Presence or absence of vitreous seeding
  • Presence of absence of retinal detachment
  • Invasion into optic nerve (prelaminar, to lamina cribrosa, retrolaminar, posterior resection margin)
  • Involvement or noninvolvement of other structures submitted
  • Margins (minimum clearance)
  • Angiolymphatic invasion
  • Tumor necrosis, calcification, DNA deposition around blood vessels, anterior chamber seeding, retinal or iris neovascularization