Juvenile xanthogranuloma - iris

Topic Completed: 1 February 2014

Minor changes: 8 April 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Juvenile xanthogranuloma iris

Nat Pernick, M.D.
Page views in 2019: 72
Page views in 2020 to date: 34
Cite this page: Pernick N. Uvea: juvenile xanthogranuloma - iris. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuveajuvenilexanthogranuloma.html. Accessed May 29th, 2020.
Definition / general
  • Iris lesion of young children causing spontaneous hyphema (hemorrhage into anterior chamber) or secondary glaucoma
  • Associated with similar skin lesions
Clinical images

AFIP images
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White tumor masses on surface of iris

Microscopic (histologic) images

AFIP images
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Infiltrative histiocytic
cells of iris and
anterior chamber angle

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Tumor invades iris stroma and anterior chamber

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Histiocytic cells with mitotic activity

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Foamy histiocytic
proliferation with
Touton giant cells

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