Juvenile xanthogranuloma - iris

Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 May 2018, last major update February 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Juvenile xanthogranuloma iris

Cite this page: Pernick, N. Uvea: juvenile xanthogranuloma - iris. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuveajuvenilexanthogranuloma.html. Accessed July 21st, 2018.
Definition / general
  • Iris lesion of young children causing spontaneous hyphema (hemorrhage into anterior chamber) or secondary glaucoma
  • Associated with similar skin lesions
Clinical images

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White tumor masses on surface of iris

Microscopic (histologic) images

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Infiltrative histiocytic
cells of iris and
anterior chamber angle

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Tumor invades iris stroma and anterior chamber

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Histiocytic cells with mitotic activity

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Foamy histiocytic
proliferation with
Touton giant cells