Lisch nodules - iris

Topic Completed: 1 October 2014

Revised: 8 April 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Lisch nodules [title] iris

Nat Pernick, M.D.
Page views in 2018: 220
Page views in 2019 to date: 175
Cite this page: Pernick N. Uvea: Lisch nodules - iris. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuvealisch.html. Accessed September 20th, 2019.
Definition / general
  • Pigmented iris hamartomas
  • Associated with neurofibromatosis type 1, also familial angiolipomatosis, a benign condition with no malignant potential (Arch Pathol Lab Med 1999;123:946)
Clinical images

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Lisch nodules

Microscopic (histologic) description
  • Dome shaped papules on anterior surface of iris consisting of aggregates of ovoid to round cells
Positive stains
Differential diagnosis
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