Lisch nodules - iris

Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 May 2018, last major update October 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Lisch nodules [title] iris

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Cite this page: Pernick, N. Uvea: Lisch nodules - iris. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuvealisch.html. Accessed January 21st, 2019.
Definition / general
  • Pigmented iris hamartomas
  • Associated with neurofibromatosis type 1, also familial angiolipomatosis, a benign condition with no malignant potential (Arch Pathol Lab Med 1999;123:946)
Clinical images

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Lisch nodules

Microscopic (histologic) description
  • Dome shaped papules on anterior surface of iris consisting of aggregates of ovoid to round cells
Positive stains
Differential diagnosis