Sarcoidosis in uvea

Topic Completed: 1 February 2014

Minor changes: 8 April 2019

Copyright: 2004-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis [title] uvea

Nat Pernick, M.D.
Page views in 2019: 23
Page views in 2020 to date: 15
Cite this page: Pernick N. Uvea: sarcoidosis in uvea. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuveasarcoidosis.html. Accessed May 28th, 2020.
Definition / general
  • Systemic granulomatous disease, usually affecting young adult blacks
  • Uvea involved in 1/3
  • May cause "mutton-fat" corneal precipitates; also granulomas in choroid, retinal perivascular inflammation with candle wax drippings near retinal vessels and retinal hemorrhages
  • Patients often have conjunctival granulomas (noncaseating)
Microscopic (histologic) description
  • Noncaseating granulomas
  • Also asteroid bodies (small, eosinophilic star shaped inclusions in epithelioid cells) or Schaumann bodies (darker ovoid inclusions)
Differential diagnosis
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