Tumor features to report - uveal tumors

Topic Completed: 1 February 2014

Minor changes: 8 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Tumor features uveal tumors

Editor's note

Nat Pernick, M.D.
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Page views in 2020 to date: 17
Cite this page: Pernick N. Uvea: tumor features to report. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/eyeuveatumorfeatures.html. Accessed June 1st, 2020.
Definition / general
  • Histologic type
  • Cell types present (for melanomas)
  • Precise anatomic location (iris, ciliary body, choroid), relative to clock hour
  • Tumor size
  • Extraocular extension
  • Growth pattern (diffuse, ring, focal)
  • Dimension of largest diameter in contact with sclera
  • Color of surface lesion and cut surface of lesion
  • Involvement or noninvolvement of other structures present
  • Margins (minimum clearance)
  • Mitotic figures per 40 high power fields
  • Presence of absence of 100 tumor infiltrating lymphocytes per 40 high power fields
  • Presence of matrix rich microcirculation associated loops, networks or parallel with cross linking structures
  • Angiolymphatic invasion
  • Presence of retinal detachment or hemorrhage
  • Involvement of intrascleral emissary channels
  • For melanomas, indicate thickness and mitotic activity, color of surface lesion
  • Other features present: drusen, neovascularization, nevi, etc.

Additional references
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