Fallopian tubes
Benign / nonneoplastic

Topic Completed: 1 March 2013

Revised: 23 August 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Fallopian tubes Benign or non-neoplastic conditions Amyloidosis

Nicole Riddle, M.D.
Page views in 2018: 166
Page views in 2019 to date: 155
Cite this page: Riddle N. Amyloidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/fallopiantubesamyloidosis.html. Accessed November 19th, 2019.
Definition / general
  • Very rare; infiltration of fallopian tube by amyloid protein, usually associated with generalized abdominal amyloid involvement
  • Renal dialysis patients, elderly, plasma cell dyscrasias
  • Arises as proteins become insoluble, are deposited in extracellular space of various tissues / organs or disrupt normal function
  • Change in the protein's secondary structure causes the protein to aggregate in insoluble form and form beta-pleated sheet
  • Amorphous eosinophilic proteins on H&E, confirmed by Congo red with apple green birefringence on polarization
  • Thioflavin T stain may be helpful
Case reports
  • 56 year old woman on renal dialysis with beta 2 microglobulin amyloidosis presenting as bilateral ovarian masses with involvement of fallopian tubes (Am J Surg Pathol 2002;26:130)
Gross description
  • May be unremarkable or show a mass lesion
Microscopic (histologic) description
  • Extracellular amorphous eosinophilic material
Microscopic (histologic) images

Images hosted on other servers:

Amyloid with Congo red staining and apple green birefringence in cardiac muscle

Back to top