Fallopian tubes
Benign or nonneoplastic conditions
Decidual reaction

Author: Nicole Riddle, M.D. (see Authors page)
Editor: Jamie Shutter, M.D.

Revised: 2 August 2017, last major update March 2013

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Fallopian tubes - Decidual reaction

Cite this page: Decidual reaction. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/fallopiantubesdecidual.html. Accessed October 19th, 2018.
Definition / general
  • Decidual reaction of subepithelial stroma similar to that seen in endometrium
  • Epithelium is often atrophic
Clinical features
  • Common at time of cesarean section (with accompanying tubal ligation) or after hormonal therapy
  • May occur more often than generally believed, 12% incidence in one study (Am J Pathol 1943;19:1043)
  • Serosal decidua formation common finding (5.5%) after tubal ligation (Am J Surg Pathol 1987;11:526)
Case reports
  • 41 year old woman with stromal and epithelial changes in fallopian tube following hormonal therapy (Hum Pathol 1980;11:583)
  • 41 year old woman with omentum sampling post caesarean section for term delivery without complications (Case of Week #285)
Microscopic (histologic) description
  • Small nodules of decidual cells covered by flattened or inflamed epithelium; affects stromal cells of lamina propria
Microscopic (histologic) images

Images stored on PathOut server

Case of Week #285

Case of Week #285 - left: PR, right: vimentin

Various images

Images hosted on other servers

Every mucosal fold is distended
by decidual cells; advanced
involution is present, leaving
most of the folds partially cystic

Distended mucosal fold is attached to wall by a relatively narrow pedicle;
tubal epithelium is flattened by compression; extensive involution is present,
leaving the fold partially cystic; remaining decidual cells are in various stages of
degeneration and vacuolated cells and ring forms are evident

Two structurally intact decidual cells
are present at tip of a mucosal fold;
the covering epithelium
is flattened

Mucosal fold is distended by
structurally well preserved decidual cells,
which vary in size and shape;
covering tubal epithelium is flattened

Group of decidual cells in a peritoneal evagination near the
mesosalpinx has vacuolated cells and ring forms; also intact
but flattened covering layer of serosal mesothelium;
overlies cuboidal mesothelium detached from underlying tissue

Involuting decidual cells, mostly peculiar,
somewhat irregular ring form