Fallopian tubes
Benign / nonneoplastic

Topic Completed: 1 April 2013

Minor changes: 13 December 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: fallopian tubes [title] AND "endometriosis"

Nicole Riddle, M.D.
Jamie Shutter, M.D.
Page views in 2019: 2,264
Page views in 2020 to date: 927
Cite this page: Riddle N, Shutter J. Endometriosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/fallopiantubesendometriosis.html. Accessed June 4th, 2020.
Definition / general
  • Presence of endometrial tissue within fallopian tube; will cycle with normal endometrium
  • Muscularis usually not involved
  • Usually also found elsewhere in pelvis
  • May represent extension of endometrium from uterine cornu (10% of women have extension to isthmus)
Clinical features
  • Symptoms depend on site and extent of disease
  • May be incidental finding or associated with abdominal / pelvic pain, infertility (due to anatomic disruption or adhesions, J Assist Reprod Genet 2010;27:441)
  • Pain medication, hormone therapy (oral contraceptive pill), surgery
Clinical images

Images hosted on other servers

Pouch of Douglas and sacrouterine ligament

Peritoneum of pelvic wall

Gross description
  • May have red nodules in wall or serosa, may be actual polyp, may have normal gross appearance
Microscopic (histologic) description
  • Endometrial glands, endometrial stroma, hemosiderin - laden macrophages: need 2 to make diagnosis
Microscopic (histologic) images

AFIP images

Dilated lymphatics at
junction of endometrial
tissue and muscle layer

Images hosted on other servers

Small cluster of
endometrial glands
and stroma with

Fallopian tube lumen on left, endometriotic nodule on right

Higher power view of endometriotic nodule

Wall of endometrioma,
note endometrial glands,
stroma and hemosiderin
laden macrophages

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