Fallopian tubes
Tumors
Female adnexal tumor of probable Wolffian origin (FATWO)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 August 2017, last major update September 2013

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PubMed Search: Female adnexal tumor of probable Wolffian origin

Cite this page: Female adnexal tumor of probable Wolffian origin. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/fallopiantubesfemaleadnexal.html. Accessed September 25th, 2017.
Definition / general
  • Rare, ~40 cases reported
  • Mean age 47 years, range 15 to 72 years
  • Nonspecific symptoms or incidental mass
  • Usually benign, no known features predictive of malignancy
Case reports
Gross description
  • Solid tumor within or hanging from broad ligament or fallopian tube by a pedicle
  • Mean 8 cm, rounded with bosselated external surface
  • Solid or cystic cut surface; gray white, tan or yellow, firm to rubbery
  • Hemorrhage or necrosis is rare
Gross images

Images hosted on PathOut server:

Broad ligament tumor of probable Wolffian origin

Microscopic (histologic) description
  • Diffuse, trabecular, tubular or sieve like patterns
  • Cells are cuboidal to columnar with minimal cytoplasm
  • Rarely abundant pale cytoplasm; nuclei small, round / oval, pale
  • May have prominent hyalinized stroma or fibrous bands that creates lobular appearance
  • Sheets of tumor cells may have a spindly appearance
Microscopic (histologic) images

Images hosted on PathOut server:

Broad ligament tumor of probable Wolffian origin

Positive stains
Negative stains
Electron microscopy description
  • Thick peritubular basal lamina, no / minimal cilia
  • Golgi apparatus, secretory granules and glycogen favor Wolffian origin