Walthard cell nests
Reviewer: Nicole Riddle, M.D. (see Reviewers page)
Editor: Jamie Shutter, M.D.
Revised: 10 April 2014, last major update September 2013
Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.
PubMed Search: Walthard cell nests [title]
- Benign epithelial cell clusters found in peri-fallopian tube tissue
- Also called transitional / urethelial cell metaplasia
- May be found anywhere in broad ligament, including ovarian hilum
- May be source of Brenner tumors or primary urethelial cell carcinomas (parafallopian tube transitional cell carcinoma) (Gynecol Oncol 2002;86:379)
- May be white/yellow nodules or cysts up to 2 mm
- Often an incidental microscopic finding
Several small yellow nodules clustered on serosa of isthmic portion of tube
- Well circumscribed, small, round collections of flat to cuboidal cells with minimal atypia
- Elliptical nuclei with prominent nuclear grooves, 1-2 small nucleoli
- May see inspissated eosinophilic secretion or mucin within lumina
- No / rare mitotic figures
Warthard cell nests at lower right
Note "coffee bean" nuclei
- CK20, uroplakin (Brenner tumors are uroplakin+)
End of Fallopian tubes > Benign/non-neoplastic > Walthard cell nests
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected]
with any questions (click here for other