Gastrointestinal stromal tumor

Gallbladder
Malignant gallbladder tumors
Gastrointestinal stromal tumor

Author: Hanni Gulwani, M.D.

Topic Completed: 1 September 2012

Revised: 15 February 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Gastrointestinal stromal tumor gallbladder

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Table of Contents

Cite this page: Gulwani H Gastrointestinal stromal tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladderGIST.html. Accessed March 20th, 2019.

Definition / general

Very rare (< 10 cases reported)
Benign or malignant behavior

Case reports

34 year old woman with right upper quadrant abdominal pain (Arch Pathol Lab Med 2002;126:481)
69 year old woman (Am J Surg Pathol 2000;24:1420)
72 year old woman with CD117- tumor (HPB Surg 2011;2011:327192)
Primary malignant gastrointestinal stromal tumor (J Gastrointest Cancer 2012;43:S151)

Microscopic (histologic) description

Bland spindle cells with hyperchromatic nuclei

Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains

CD117, vimentin, variable CD34

Negative stains

Smooth muscle actin, desmin, myoglobin, cytokeratin, S100