Extrahepatic bile ducts
Carcinoid tumor of extrahepatic bile ducts

Topic Completed: 1 September 2012

Revised: 20 September 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Carcinoid tumor[TIAB] extrahepatic bile ducts

Hanni Gulwani, M.B.B.S.
Page views in 2019: 116
Page views in 2020 to date: 8
Cite this page: Gulwani H. Carcinoid tumor of extrahepatic bile ducts. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/gallbladdercarcinoidextrahepatic.html. Accessed February 18th, 2020.
Definition / general
  • 0.3% of tumors in extrahepatic bile ducts
  • 2/3 women, mean 50 years old, range 37 - 67 years
  • No systemic endocrine symptoms
  • Rarely associated with MEN1 and von Hippel-Lindau syndrome
  • Indolent course with long survival even if nodal or hepatic metastases (Am J Surg Pathol 2000;24:1501)
  • Tumor size (> 2 cm) appears to be the best predictor of aggressive behavior (Arch Pathol Lab Med 2010;134:1075)
Case reports
Gross images

Images hosted on other servers:

Clear cell carcinoid tumor
of the distal common bile
duct: golden yellowish
polypoid mass

Microscopic (histologic) description
  • Nests, cords or trabeculae of small cells with granular chromatin
  • Perineural and vascular invasion is common
Microscopic (histologic) images

Images hosted on other servers:

Various images

31 year old woman with von Hippel-Lindau syndrome

Positive stains
Negative stains
Electron microscopy description
  • Numerous membrane bound, round, neurosecretory granules
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