Extrahepatic bile ducts

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Extrahepatic bile ducts

Tumors

Cystadenoma

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 15 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● More uncommon in extrahepatic biliary system than in liver
● Extremely rare in gallbladder
● Usually women ages 42-55 years
● Resembles pancreatic cystadenoma

Case reports
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● 54 year old woman with extrahepatic biliary cystadenoma with mesenchymal stroma (J Gastrointestin Liver Dis 2011;20:209)
● 62 year old woman with intrahepatic cystadenoma that extended into common biliary duct (BMJ Case Rep 2012 Apr 4;2012)

Treatment
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● Excision, may recur or become malignant

Gross description
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● Unilocular or multilocular
● Well defined cystic masses with serous, mucinous, bilious, hemorrhagic or mixed fluid
● Outer fibrous wall
● Inner surface is smooth, granular or trabeculated

Gross images
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Multilocular cyst

With multiple tumor nodules

Micro description
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● Multiple locules lined by biliary-type cuboidal or columnar epithelium
● Stroma is cellular, resembling ovarian stroma in 85%, surrounded by hyalinized fibrous tissue
● 13% have dysplastic changes

Micro images
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Various images

End of Extrahepatic bile ducts > Tumors > Cystadenoma

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